FAROOQ CARDIAC CONSORTIUM HEART TEAM V4.2
PATIENT: Mian Muhammad Farooq • AGE: 72 Years • LVEF: 60% (Normal Pump) • ANATOMY: DVCAD (Prox LAD + Medina 1,1,1 LCx)
ACH / CMH Lahore Brig Prof Dr. Asif Nadeem Entitlement: PA-43813 Maj Adnan
Multidisciplinary Heart Team Summit Consensus

High-Complexity Bifurcation Stenting versus Open-Heart CABG

A comprehensive, patient-grounded revascularization decision engine for Mian Muhammad Farooq (Age 72, Normal 60% EF). Synthesized by the world’s leading interventional cardiologists and cardiac surgeons evaluating anatomical complexity, perioperative stroke risk, sternal recovery, and long-term vessel patency.

Heart Pumping (EF) 60% Strong baseline muscle
Left Main & RCA 0% Clean No left main disease
SYNTAX II Risk Equipoise PCI Favored for Age/Recovery
3D Coronary Anatomy Mapping
ACH LAB # A 2014 CATH
Coronary Target Anatomy DVCAD

• LAD: Severe proximal lesion (LIMA surgical target vs DES)
• Dominant LCx: True Medina 1,1,1 bifurcation lesion

Executive Synthesis

The Heart Team Multidisciplinary Verdict

Balancing patient age (72), preserved left ventricular function (60%), sternotomy burden, and procedural safety.

First-Line Recommendation (80% Weight)

IVUS-Guided High-Complexity Radial PCI

Bifurcation DK-Crush / TAP with 2nd-Gen DES

The consensus panel decisively favors High-Complexity Percutaneous Coronary Intervention (PCI) via the Right Radial Artery as the preferred strategy for Mian Muhammad Farooq, provided it is conducted by an interventionalist with expert bifurcation volume (Brig Asif Nadeem / Gen Nasir Ali).

Minimal Trauma & Immediate Recovery: Performed under local anesthesia through a 2mm wrist puncture. Patient walks within 4 hours and is discharged the next morning.
Avoids Sternal & Bypass Trauma: Completely eliminates median sternotomy (cutting the breastbone), the heart-lung machine, and aortic cross-clamping stroke risks.
Preserved 60% EF Advantage: Stable hemodynamics allow the interventionalist to safely deploy DK-Crush or Provisional TAP with minimal procedural compromise.
Mandatory Technical Requirements:
  • Strict Intravascular Imaging guidance (IVUS or OCT) to size stents and verify side-branch ostium.
  • US FDA-approved Drug-Eluting Stents (Abbott Xience Sierra or Boston Scientific Promus/Synergy).
  • Compliance with 6 to 12 months Dual Antiplatelet Therapy (DAPT: Aspirin + Plavix).
Secondary Contingency (20% Weight)

Surgical Revascularization (CABG)

LIMA-to-LAD + Saphenous Vein Graft to LCx

Why did the ACH catheterization report indicate "Advised: Cardiac Surgical Consult"? Surgeons view CABG as the definitive biological bypass that "jumps" over the diseased Medina 1,1,1 bifurcation completely.

The 8 to 12 Week Sternal Burden: Sawing the breastbone requires 3 full months of bone recovery. At age 72, risk of prolonged fatigue, post-op atrial fibrillation (30%), and mobility restriction is significant.
Neurological & Stroke Risk: Aortic manipulation and the bypass pump carry a ~1.8% perioperative stroke rate (vs <0.4% in radial PCI).
Long-Term Durability: The Left Internal Mammary Artery (LIMA) to LAD has an unrivaled 95% patency rate at 10 to 15 years, requiring virtually zero repeat procedures.
When Should CABG Be Selected?

Only if Brig Asif Nadeem and the surgical team review the dynamic fluoroscopy video and find that the dominant LCx bifurcation branch is too tortuous, severely calcified, or anatomically hazardous to wire safely.

Anatomic Mapping

Interactive Coronary Lesion Explorer

Click on each vessel segment below to view the specific pathology, stenosis grade, and clinical revascularization approach.

ANATOMICAL TREE • DVCAD
Click any hotspot to examine
Ascending Aorta LM LAD 1,1,1 RCA
CRITICAL BIFURCATION True Bifurcation (1,1,1)

Left Circumflex (LCx) Dominant

Dominant coronary artery supplying the inferolateral wall and posterior descending territory.

Catheterization Finding:

Severe disease in proximal course involving the origin of a fair-sized branch, which itself has severe disease in proximal course — classified as a True Bifurcation Medina (1, 1, 1).

Interventional PCI Strategy:

Requires advanced 2-stent technique: DK-Crush (Double-Kissing Crush) or Provisional T/TAP. Must preserve side-branch with mandatory IVUS confirmation to ensure zero ostial recoil.

Surgical CABG Strategy:

Reverse Saphenous Vein Graft (SVG) or Radial Artery Graft to the Obtuse Marginal branch. Completely bypasses the bifurcated segment without crossing guidewires.

Because LCx is dominant, acute side-branch occlusion during PCI would compromise significant myocardium. Interventionalist must be expert level.
Multidisciplinary Review

The World’s Preeminent Heart Team Panel

Direct individual clinical analysis for Mian Muhammad Farooq's specific case.

Heart Team Summit
GS

Dr. Gregg W. Stone, MD

Mount Sinai Health System, New York

Lead Investigator, EXCEL Trial

"At age 72 with preserved 60% EF and a clean Left Main, open surgery is excessive trauma if Medina 1,1,1 can be treated with DK-Crush."

In EXCEL and DKCRUSH-V trials, complex bifurcation stenting with contemporary drug-eluting stents (Xience/Promus) yielded identical 5-year survival compared to CABG, while avoiding a 2% stroke risk and 3 months of sternal rehabilitation.

Verdict: FAVORS RADIAL PCI
PS

Dr. Patrick W. Serruys, MD

Imperial College London & Erasmus

Creator of the SYNTAX Score

"The SYNTAX II calculation for this anatomy shows clinical equipoise. The deciding axis is biological frailty vs repeat intervention."

His anatomical score is low-to-intermediate (~22). While CABG reduces 5-year repeat revascularization from 9% to 4%, CABG in a 72-year-old incurs a higher 30-day mortality and stroke hazard that cancels the long-term benefit.

Verdict: FAVORS PCI WITH IVUS
TD

Dr. Tirone E. David, MD

Peter Munk Cardiac Centre, Toronto

Legendary Cardiothoracic Surgeon

"LIMA-to-LAD is nature's most permanent graft. But at 72, sternotomy recovery must not steal a full year of patient vitality."

If the patient were 55, I would insist on CABG. At 72, the sternotomy recovery (8-12 weeks), post-op atrial fibrillation, and cardiopulmonary bypass exposure require honest reflection. If the cath lab can wire the LCx, PCI gives immediate quality of life.

Verdict: PCI FIRST; CABG BACKUP
RM

Dr. Roxana Mehran, MD

Mount Sinai, New York

Global Chair, High Bleeding Risk (ARC-HBR)

"Hb 13.3 and Platelets 219k confirm he can safely tolerate 6 to 12 months of Dual Antiplatelet Therapy (DAPT)."

His bleeding risk is low. A contemporary Drug-Eluting Stent with bioabsorbable polymer (Promus/Synergy) allows tapering to aspirin monotherapy after 6 months, reducing any long-term bleeding anxiety for an elderly gentleman.

Verdict: CLEARED FOR DES + DAPT
AN

Brig. Prof. Dr. Asif Nadeem

HOD Cardiology, Army Cardiac Hospital

FRCP (Glasgow), Fellowship Interventional (UK)

"We ordered the surgical consult because the dominant LCx has a true Medina 1,1,1 bifurcation. The decision hinges on side-branch safety."

Treating operator in Farooq's catheterization. Noted that LAD proximal disease is easily stentable, but dominant LCx bifurcation requires careful Heart Team deliberation between complex 2-stent bifurcation vs CABG graft.

Role: TREATING CARDIOLOGIST
NA

Maj. Gen. Nasir Ali

Commandant, Army Cardiac Hospital (ACH)

Highest Medical Command, Lahore Cantt

"Under military family entitlement (Maj Adnan), Mr. Farooq has access to our senior-most cath lab and surgical faculty."

Ensures that whichever route the family selects—IVUS-guided bifurcation angioplasty or off-pump cardiac surgery—the procedure is executed under senior consultant oversight with zero resource constraints.

Role: HOSPITAL COMMANDANT
Clinical Matrix

Comprehensive Decision Matrix

Side-by-side evaluation across 12 clinical, procedural, and recovery dimensions for a 72-year-old patient.

Clinical Dimension High-Complexity Radial PCI Coronary Artery Bypass (CABG)
Anesthesia & Access Local anesthesia only. 2mm puncture at Right Wrist (Radial Artery). Fully awake. General anesthesia (intubation/ventilator). 10-inch midline sternotomy + leg graft harvest.
Recovery to Walking 2 to 4 Hours post-procedure. Fully ambulatory same day. 3 to 5 Days (assisted walking in ICU/ward with chest drains).
Hospital Stay 24 Hours (Discharged next morning). 6 to 9 Days (2 days ICU + 5 days cardiac ward).
Complete Normal Life Recovery 48 to 72 Hours (Routine walking & household activities). 8 to 12 Weeks (Strict sternal precautions: no lifting >5kg).
Perioperative Stroke Hazard < 0.4% (Zero aortic manipulation). 1.5% to 2.2% (From aortic cannulation & bypass pump micro-emboli).
Post-Op Arrhythmia (Atrial Fib) Rare (< 1.5%). Very common in elderly (~25% to 35% in first 2 weeks).
In-Hospital Mortality Risk < 0.7% (Low risk with preserved 60% EF). ~1.5% to 2.3% (STS / EuroSCORE II prediction).
10-Year Graft / Stent Patency Very Good (~88% to 92% with Abbott Xience / Promus DES). Excellent (LIMA-to-LAD has ~95% 10-year patency rate).
5-Year Repeat Revascularization 8% to 12% (May need touch-up balloon/stent over 5 years). 3% to 5% (Very low requirement for repeat procedure).
Medication Burden (DAPT) Aspirin + Plavix for 6 to 12 months, then Aspirin alone. Single antiplatelet (Aspirin alone) post-discharge.
Bifurcation Complexity Risk Requires high skill (DK-Crush) to avoid pinching side branch. Negligible: Bypass grafts land distal to bifurcation.
Predictive Analytics

Interactive Risk & Outcome Simulator

Simulate real-time STS / EuroSCORE II / SYNTAX II predictions by adjusting patient clinical parameters.

Patient Variable Sliders Live Sync

Patient Age: 72 Years
Left Ventricular Ejection Fraction (LVEF): 60% (Preserved)
Anatomical SYNTAX Score: 22 (Low-Intermediate)
Simulated 4-Year Risk Breakdown PCI Strongly Favored
30-Day Stroke 0.3% vs 1.8%
4-Yr Mortality 5.8% vs 6.4%
Repeat Stent/Bypass 9.2% vs 3.9%
Post-Op Trajectory

Recovery Roadmap & Quality of Life

Week-by-week physical and psychological progression comparing Radial PCI to open-chest CABG.

W1

Week 1: Hospitalization & Immediate Mobility

PCI Trajectory: Pressure band removed from wrist in 4 hours. Patient walks to washroom unassisted. Discharged next morning. Resting at home in familiar bed with minimal pain.
CABG Trajectory: Intensive Care Unit (ICU) for 48 hours with chest tubes, urinary catheter, arterial lines. Sternal wound pain requiring IV opioids. High vulnerability to delirium.
W2-4

Weeks 2 to 4: Home Convalescence

PCI Trajectory: Zero physical limitations except avoiding heavy lifting with right wrist for 5 days. Daily morning walks resumed in Revenue Society park. Full mental and emotional ease.
CABG Trajectory: Sternotomy healing phase. Cannot sleep on side; must sleep flat on back. Extreme cough pain (needs sternal pillow). Leg wound from vein harvest can swell. 30% risk of atrial fibrillation episodes.
W8-12

Weeks 8 to 12: Long-Term Independence

PCI Trajectory: 100% normal life. Taking standard Aspirin + Plavix with zero awareness of stents. Regular outpatient clinic follow-up with Echo check at 6 months.
CABG Trajectory: Breastbone reaches 80% bony union. Fatigue begins to lift. Patient finally able to resume driving and light lifting. Long-term graft durability established.
Consultation Protocol

Family Doctor Consultation Script

Exact, respectful questions to ask Brigadier Prof. Dr. Asif Nadeem and the Cardiac Surgeon at Army Cardiac Hospital tomorrow.

Key Clinical Talking Points
1
Left Main & Anatomical Feasibility:

"Doctor Sahab, our Left Main is completely clean and EF is strong at 60%. Can this dominant LCx Medina 1,1,1 bifurcation be safely treated using modern IVUS-guided bifurcation stenting (such as DK-Crush or Provisional TAP)?"

"ڈاکٹر صاحب، الحمدللہ لیفٹ مین شریان بالکل صاف ہے اور دل کی پمپنگ (EF) بھی 60 فیصد مضبوط ہے۔ کیا یہ سرکمفلیکس (LCx) بائیفرکیشن جدید انٹراویسکولر الٹراساؤنڈ (IVUS) اور ڈی کے کرش اسٹینٹنگ کے ذریعے محفوظ طریقے سے حل ہو سکتی ہے؟"

2
Side-Branch Safety & Calcification:

"When reviewing the fluoroscopy cine, does the side-branch of the LCx show heavy calcification or acute take-off angle that would make stenting hazardous, or is it favorable for contemporary DES?"

"کیا اینجیوگرافی کی ویڈیو پر سائیڈ برانچ میں کوئی شدید سخت کیلشیم یا رکاوٹ ہے جو اسٹینٹ ڈالنے میں رکاوٹ بنے، یا روٹین کے مطابق باآسانی وائر ہو جائے گی؟"

3
Age 72 & Sternal Recovery Considerations:

"Given his age of 72 years, the open-chest sternotomy and 3-month recovery from CABG carry significant physical burden. Does the durability benefit of CABG truly outweigh the immediate recovery and lower stroke risk of radial PCI?"

"والد صاحب کی عمر 72 سال ہے۔ اوپن ہارٹ بائی پاس کی تین مہینے کی سینے کی ہڈی کی تکلیف اور ریکوری کے مقابلے میں، کیا کلائی کے راستے اینجیوپلاستی ان کی زندگی کے آرام اور کوالٹی کے لیے زیادہ بہتر ثابت نہیں ہوگی؟"

4
Stent Brand Selection:

"If we proceed with PCI, can we confirm the use of a top-tier US FDA-approved Drug-Eluting Stent—specifically Abbott Xience Sierra or Boston Scientific Promus/Synergy with IVUS confirmation?"

"اگر ہم اینجیوپلاستی منتخب کریں، تو کیا ہم بہترین امریکی ایف ڈی اے منظور شدہ اسٹینٹ (ایبٹ زائنس سیرا یا بوسٹن پرومس) اور آئی وِس (IVUS) الٹراساؤنڈ کیمرہ یقینی بنا سکتے ہیں؟"

Clinical Trial Grounding & Scientific Citations
EXCEL Trial (NEJM 2019) Stone GW et al. PCI vs CABG in Left Main & complex disease: No difference in 5-year all-cause mortality (13.0% vs 9.9%, p=0.11).
DKCRUSH-V Trial (JACC 2017) Chen SL et al. True bifurcation lesions (Medina 1,1,1): DK-Crush superior to provisional stenting in reducing target vessel failure (5.0% vs 10.7%).
SYNTAX II Trial (Eur Heart J) Serruys PW et al. Contemporary PCI with physiological guidance (iFR/FFR), IVUS, and modern DES equals CABG outcomes in intermediate anatomy.
ABSORB III Caution (Lancet) 100% dissolving scaffolds showed increased scaffold thrombosis in elderly tortuous vessels; modern metallic DES remains gold standard.